Thanks Turmel. I will have to dig into that code you posted.
I was hoping some one would get back to me on how to configure the Instrument Interface to do this Continuous Serial Port monitoring. I believe its a feature(Accept Unsolicited Request) of Instrument Interface based on what I heard at the 2:00 min mark from this video. http://www.sepasoft.com/video-library/5-1-2-serial-settings/
The company I work for has already purchased an Instrument Interface license, I will try to give Sepasoft a call. See if they solved this problem or I have to do the custom code solution.