Yes. As long as your computer has the prerequisite graphic processing hardware, the designer will work great with two 4k 32" monitors; many of us are using them.
Here is a separate post where this sort of thing is discussed:
I have a 27" 4K and a 27" 2K. Just make sure you set windows scaling to 100%, as always, and you'll be good. If you don't want to go 100%, dont waste your money; get a lower res monitor