Bypass Store and Forward Transaction Group option

I notice if I add a new Stored Procedure transaction group then by default the “Bypass Store And Forward” option is ticked.

Is there a reason for this? Can the Store and Forward mechanism cope with Stored Procedures if I were to untick the box?

(in my specific case the SPs are only taking input parameters and are not returning any values)

Looking at the code for this and it appears that you can use the store and forward as long as there are no output or return parameter mappings.