Certainly! Essentially, the “insert new record” button is disabled if your group mode is set to anything other than OPC->DB.
The reason is: All of the other modes require reading from the database. It would make no sense to insert a row in this case, you would always be reading the same default values.
That said, it is not uncommon to have one group reading the last row of the table, and then another group that periodically (or on a trigger) inserts a new row, causing the first group to now see and update that one instead.
Hope this helps,