KepServerEX V4 to V5

I will be upgrading from KepServerEX version 4 to version 5 soon and would like to know if there have been any issues with FactorySQL. I am hoping this is a seemless change and FactorySQL refreshes the OPC server correctly and that there are no issues with OPC items. Or, will I have to update all server paths for each item?

It is a seamless change. You may have to change the OPC Server for the items but the item paths are the same. In FactorySQL you do have a search and replace option to change the server if needed.